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2022年

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1

Primate gastrulation and early organogenesis at single-cell resolution

Nature

2022 Dec;612(7941):

732-738

2

A sustainable mouse karyotype created by programmed chromosome fusion

Science

2022;377(6609)

967-975

3

Dynamics of DNA hydroxymethylation and methylation during mouse embryonic and germline development

Nature Genetics

2022 Dec 20

 

4

Depletion of BATF in CAR-T cells enhances antitumor activity by inducing resistance against exhaustion and formation of central memory cells

Cancer Cell

2022;40(11)

1407-1422.e7

5

Transcription–replication conflicts in primordial germ cells necessitate the Fanconi anemia pathway to afeguard
genome stability

PNAS

Vol. 119 No. 34 e2203208119

1-11

6

Lipid metabolism dysfunction induced by age-dependent DNA methylation accelerates aging

Signal Transduct Target Ther

2022;7(1)

162

7

Mutations of MSH5 in nonobstructive azoospermia (NOA) and rescued via in vivo gene editing

Signal transduction and targeted therapy

2022;7(1)

1

8

Dissecting the fate of 1 Foxl2-expressing cells in fetal ovary using lineage tracing and Single-Cell Transcriptomics

Cell Discovery

2022 Dec 27;8(1):139

139

9

Human SERPINA3 induces neocortical folding and improves cognitive ability in mice

Cell Discovery

2022;8(1)

124-143

10

A differentiation roadmap of murine placentation at single-cell resolution

Cell Discovery.

2022

 

11

Metagenomic discovery of novel CRISPR-Cas13 systems

Cell Discovery

2022;8(1)

107

12

Lateral plate mesoderm cell-based organoid system for NK cell regeneration from human pluripotent stem cells

Cell Discovery

2022 Nov 8;8(1)

121

13

Ultrasensitive Ribo-seq reveals translational
landscapes during mammalian oocyte-to-embryo
transition and pre-implantation development

Nature Cell Biology

VOL 24 | June 2022

968–980

14

Decoding the temporal and regional specification of
microglia in the developing human brain

Cell Stem Cell

2022;29(4)

620-634

15

Synergistic engineering of CRISPR-Cas nucleases enables robust mammalian genome editing

The Innovation

2022;3(4)

420-428

16

Deciphering the dynamics of the ovarian reserve in cynomolgus monkey through a quantitative morphometric study

Sci Bull

2022, 67(18)

1854-1859

17

Cnot8 eliminates naive regulation networks and is
essential for naive-to-formative pluripotency transition

Nucleic Acids Research

2022, Vol. 50, No. 8

4414–4435

18

Remodeling of maternal mRNA through poly(A) tail orchestrates human oocyte-to-embryo transition

nature structural & molecular biology

 

 

19

A Human-specific De Novo Gene Promotes Cortical Expansion and Folding

Advanced Science

 

 

20

Endothelial Cells Mediated by UCP2 Control the
Neurogenic-to-Astrogenic Neural Stem Cells Fate Switch
During Brain Development

Advanced Science

 2022;9(18)

e2105208

21

Pharmacological Perturbation of Mechanical Contractility Enables Robust Transdifferentiation of Human Fibroblasts into Neurons

Advanced Science

2022;9(13)

e2104682

22

A Uterus-Inspired Niche Drives Blastocyst Development to the Early Organogenesis

Advanced Science

2022;9(28):

e2202282.

23

Genetically Encoded Double-Stranded DNA-Based Nanostructure Folded by a Covalently Bivalent CRISPR/dCas System

Journal of the American Chemical Society

2022;144(14)

6575-6582

24

Oxidative phosphorylation safeguards pluripotency via UDP-N-acetylglucosamine

Protein&Cell

 

 

25

A framework for the responsible reform of the 14-day rule in human embryo research

Protein Cell

2022;13(8)

552-558

26

Identification and characterization of BEND2 as a key regulator of meiosis during mouse spermatogenesis

Science Advances

2022;8(21)

eabn1606

27

Spatial metabolomics reveals skeletal myofiber subtypes

Science Advances

in press

 

28

Acetate supplementation restores cognitive deficits
caused by ARID1A haploinsufficiency in excitatory
neurons

EMBO MOLECULAR MEDICINE

2022;14(12)

 

29

Microglia homeostasis mediated by epigenetic ARID1A regulates neural progenitor cells response and leads to autism-like behaviors

Molecular Psychiatry

 Online

1-15

30

Loss of microglial EED impairs synapse density, learning, and
memory

MOLECULAR PSYCHIATRY

2022;27(7)

2999-3009

31

Epg5 deficiency leads to primary ovarian insufficiency due to WT1 accumulation in mouse granulosa cells

Autophagy

doi.org/10.1080/15548627.2022.2094671

1-16

32

Hypoxic stress disrupts HGF/Met signaling in human trophoblasts: implications for the pathogenesis of preeclampsia

J Biomed Sci

2022;29(1)

8

33

Single-cell analysis of human testis aging and correlation with elevated body mass index

Developmental Cell

2022;57(9)

1160-1176

34

Pathogenesis of sarcopenia and the relationship with fat mass: descriptive review

Journal of Cachexia Sarcopenia and Muscle

2022 Apr;13(2)

781-794

35

Maternal EHMT2 is essential for homologous chromosome segregation by regulating Cyclin B3 transcription in oocyte meiosis.

Int J Biol Sci

2022;18(11)

4513-4531

36

Computer-aided engineering of CRISPR-Cas proteins for enhanced human genome editing

Sci China Life Sci

 

 

37

Gene editing and its applications in biomedicine

Sci China Life Sci

2022;65(4)

660 - 700

38

One-step base editing in multiple genes by direct embryo injection for pig trait improvement

SCIENCE CHINA Life Sciences

2022,65 (4)

739-752

39

Integration of single-cell transcriptome and chromatin accessibility of early gonads development among goats, pigs, macaques, and humans

Cell Reports

2022;41(5)

111587

40

Endothelial cell sregulated by RNF20 orchestrate the proliferation and differentiation of neural precursor cells during embryonic development

Cell Reports

2022;40(11)

111350

41

BNIP3 (BCL2 interacting protein 3) regulates pluripotency by
modulating mitochondrial homeostasis via mitophagy

CELL DEATH & DISEASE

2022;13(4)

1-8

42

BNIP3-dependent mitophagy safeguards ESC genomic integrity via preventing oxidative stress-induced DNA damage and protecting homologous recombination

CELL DEATH & DISEASE

2022;13(11)

1-10

43

Generation of immunodeficient pig with hereditary tyrosinemia type 1 and their preliminary application for humanized liver

 Cell& Biosciense

2022;12(1)

12

44

MicroRNA-202 safeguards meiotic progression
by preventing premature SEPARASE-mediated
REC8 cleavage

EMBO Reports

2022;23(8)

e54298

45

The human FOXM1 homolog promotes basal
progenitor cell proliferation and cortical folding
in mouse

EMBO Reports

2022;23(3)

e53602

46

Supplementation of mitochondria from endometrial mesenchymal stem cells improves oocyte quality in aged mice.

Cell Proliferation

2022 Dec 8

e13372

47


An RNA methylation code to regulate protein translation and cell fate

Cell Proliferation

2022 May;55(5)

e13224.

48

Machine learning-based phenotypic screening for postmitotic growth inducers uncover vitamin D3 metabolites as small
molecule ribosome agonists

Cell Proliferation

2022 May;55(5)

e13214

49

The Metabaging Cycle

Cell Proliferation

2022 Mar;55(3)

e13197

50

Enhancing targeted transgene knock-ins by donor recruitment

Cell Proliferation

2022;55(1)

e13163

51

Abnormal microglial polarization induced by Arid1a deletion
leads to neuronal differentiation deficits

Cell Proliferation

2022;55(11)

 

52

Insulin-like growth factor 2 mRNA-binding protein 2-regulated alternative splicing of nuclear factor 1 C-type causes excessive granulosa cell proliferation in polycystic ovary syndrome

Cell Proliferation

2022 ,55(4)

e13216

53

Cellular and molecular atlas of the placenta from a COVID-19 pregnant woman infected at mid-gestation highlights the defective impacts on fetal health

Cell Proliferation

2022;55(4)

e13204

54

Developing standards to support cell technology applications

Cell Proliferation

2022;55(4)

1-2

55

Requirements for Human Induced Pluripotent Stem Cells

Cell Proliferation

2022;55(4)

e13182

56

Influence of feeder cells on transcriptomic analysis of pluripotent stem cells

Cell Proliferation

2022;55(2):18

e13189

57

Manufacturing with pluripotent stem cells (PSConf 2021): Key issues for future research and development

Cell Proliferation

2022;55(8)

e13301

58

Rational engineering of adeno-associated virus capsid enhances human hepatocyte tropism and reduces immunogenicity.

Cell Proliferation

2022;55(12)

e13339

59

Human ESC-derived immunity- and matrix- regulatory cells ameliorated white matter damage and vascular cognitive impairment in rats subjected to chronic cerebral hypoperfusion

Cell Proliferation

2022;55(5)

e13223

60

SRSF10 is essential for progenitor spermatogonia expansion by regulating alternative splicing.

Elife

2022 Nov 10;11

e78211

61

KW-2449 and VPA exert therapeutic effects on human neurons and cerebral organoids derived from MECP2-null hESCs

STEM CELL RESEARCH & THERAPY

2022;13(1)

534

62

Single-cell transcriptomics reveals the cell fate transitions of human dopaminergic progenitors derived from hESCs

 Stem Cell Research& Therapy

2022;13(1)

 

63

Intranasal Administration of Agomir-let-7i Improves Cognitive
Function in Mice with Traumatic Brain Injury

CELLS

2022;11(20)

 

64

The epigenetic state of EED-Gli3-Gli1 regulatory axis controls embryonic
cortical neurogenesis

STEM CELL REPORTS

2022;17(9)

2064-2080

65

CCDC38 is required for sperm flagellum biogenesis and male fertility in mice

Development

 2022 ;149(11)

1-11

66

Dynamic profiling and functional interpretation of histone lysine
crotonylation and lactylation during neural development

DEVELOPMENT

2022;149(14)

 

67

PPP4C facilitates homologous recombination DNA repair by dephosphorylating PLK1 during early embryo development.

 Development.

2022;149(10)

dev200351

68

The Regulation of Gonadal Somatic Cell Differentiation in Humans

Genomics Proteomics Bioinformatics

2022;20(2)

219-222

69

Identification of a heterozygous variant of ZP2 as a novel cause of empty follicle syndrome in humans and mice.

Hum Reprod

2022;37(4)

859-872

70

Chemical Pretreatment Activated a Plastic State Amenable to Direct Lineage Reprogramming

Frontiers in Cell and Developmental Biology

2022;10

865038

71

A Single-Cell Characterization of Human Post-implantation Embryos Cultured In Vitro Delineates Morphogenesis in Primary Syncytialization

Front Cell Dev Biol

2022,15;10

835445

72

LMNA Determines Nuclear Morphology During Syncytialization of Human Trophoblast Stem Cells

Front Cell Dev Biol

2022 ,11;10

836390

73

The diversity of trophoblast cells and niches of placenta accreta spectrum disorders revealed by single-cell RNA sequencing

Front Cell Dev Biol

2022 Nov 7;10

1044198

74

Evaluating mitophagy in embryonic stem cells by using fluorescence-based imaging

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY

2022;10:910464

1-9

75

Single-Cell Transcriptomics of Proliferative Phase Endometrium: Systems Analysis of Cell-Cell Communication Network Using CellChat

Frontiers in Cell and Developmental Biology

2022;10

919731

76

Development and Application of CRISPR-Cas Based Tools

Frontiers in Cell and Developmental Biology

2022;10

834646

77

Gene editing monkeys:
Retrospect and outlook

Frontiers in Cell and Developmental Biology

2022;13(1)

 

78

Continual Deletion of Spinal Microglia Reforms Astrocyte Scar Favoring Axonal Regeneration

Frontiers In Pharmacology

2022;13

881195

79

Somatic cell-derived BMPs induce premature meiosis in male germ cells during the embryonic stage by upregulating Dazl expression

The FASEB Journal

2022;36(2):e22131

1-14

80

The function of Foxo1 in spermatogonia development is independent of PI3K/PTEN signaling

The FASEB Journal

2022;36(10):e22522

1-10

81

BCAS2 is involved in alternative splicing and mouse oocyte development

FASEB Journal

2022 Feb;36(2)

e22128

82

Kinetochore scaffold 1 regulates SAC function during mouse oocyte meiotic maturation.

FASEB J

2022;36(3)

e22210

83

Loss of circSRY reduces γH2AX level in germ cells and impairs mouse spermatogenesis

Life Science Alliance

2022;6(2)

e202201617

84

Infection of SARS-CoV-2 causes severe pathological changes in mouse testis.

J Genet Genomics.

6:S1673-8527(22)00255-7

1-21

85

Cytochrome P450 26A1 regulates the clusters and killing activity of NK cells during the peri- implantation period

J Cell Mol Med.

2022;26

2438–2450.

86

A mouse model of neurodegeneration induced by blade penetrating stab wound to the hippocampus

BIOLOGY-BASEL

2022;11(9)

 

87

Fancb deficiency causes premature ovarian insufficiency in mice

Biol Reprod

2022;12;107(3)

790-799

88

The functions of Wt1 in mouse gonad development and somatic cells differentiation

Biol Reprod

25;107(1):269-274.

1-11

89

De novo programming: establishment of epigenome in mammalian oocytes

Biology of Reproduction

2022;107(1)

40-53

90

In vitro investigation of mammalian peri-implantation embryogenesis

Biology of Reproduction

2022 Mar 16

205–211

91

Advances in haploid embryonic stem cell research

Biology of Reproduction

2022;107(1)

250-260

92

Current status of clinical trials assessing mesenchymal stem cell therapy for graft versus host disease: a systematic review

 Stem Cell Research& Therapy

2022;13(1)

93

93

Every road leads to Rome: therapeutic effect and mechanism of the extracellular vesicles of human embryonic stem cell-derived immune and matrix regulatory cells administered to mouse models of pulmonary fibrosis through different routes

 Stem Cell Research& Therapy

2022;13(1)

163

94

Current understanding in deciphering trophoblast cell differentiation during human placentation

Biol Reprod

2022,25;107(1)

317-326

95

The mystery of the life tree: the placentas

Biol Reprod

2022;107(1)

301-316

96

Human mesenchymal stem cells

 Cell Proliferation

2022;55(4)

e13141

97

Progress in modern reproductive biology research in China

Biology of Reproduction

2022;107(1)

3-11

98

Responsible governance of human germline genome editing in China

Biology of Reproduction

2022;107(1)

261-268

99

MAPRE2 regulates the first meiotic progression in mouse oocytes.

Exp Cell Res

2022;416(1)

113135

100

Generation of Human Trophoblast Stem Cell-Dependent Placental In Vitro Models.

Methods in Molecular Biology

 2022 Dec 15

101

Workflow for Performing Genetic Manipulation in Human Trophoblast Stem Cells Using CRISPR/Cas9 Technology.

Methods in Molecular Biology

2022 Dec 15

102

Elucidating the dynamics of polypeptide hormones in the physiological and preeclampsic placental trophoblast cells across gestation at single-cell level

Life Medicine

2022